The success that away teams have enjoyed in this fixture in recent seasons makes for a compelling betting angle on Thursday evening. For that reason, we will be siding with Bournemouth to land a second straight victory at St Mary’s this week.
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The Cherries also have a poor record in midweek fixtures in the Premier League, as they have gone nine without a victory. Over that period, they have lost on seven occasions, and they have failed to win in five midweek matches in the Premier League this season. 
Southampton landed a 1-0 win in the previous clash between the sides this season, and they are looking for a first league double over the Cherries since their League One campaign in 2010-11. Bournemouth won their previous visit to St Mary’s, and the away side has landed victories when these sides have clashed in each of the last four. 
Southampton will be craving a first league win in over a month this week, as they look to build on their very impressive showing against Arsenal last Friday. The Saints were good value for maximum points in that fixture, but a late collapse saw the league leaders pick up a point at the Emirates. The Saints remain bottom of the standings after that point, and they are four points from safety with six games of the season remaining. 
Bournemouth appeared to be cruising toward safety after winning two on the bounce. However, they were brought back down to earth on Sunday, as they were thumped 4-0 by West Ham United at the Vitality Stadium. That defeat means that they sit just five points clear of the drop zone. 

Southampton vs Bournemouth Head to Head 

Southampton at least ended a three-game losing run with a draw last week, but they have disappointed at home throughout this season. They have already lost ten matches at St Mary’s this term, which is their joint-highest tally in a single Premier League campaign. They have also recorded fewer home wins and points than any other side in the top-flight. 

Southampton vs Bournemouth Prediction 

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A massive game at the bottom of the Premier League standings is set for Thursday, as Southampton desperately chase victory in their battle to stay in the top-flight. Bournemouth are the visitors, as they look to recover following a big home defeat against West Ham.